About the Role
This position will focus on the design and development of both a small-molecule SELEX and a proprietary aptamer selection pipeline, in the context of an early-stage AI drug discovery company. The SELEX pipeline will be an integral part of our AI-wet-lab feedback loop. The position may also offer outstanding opportunities to work on state-of-the-art high-throughput platforms, automation and other biophysical studies. This role is ideally suited for a motivated experimental scientist who is passionate about pharmaceuticals and technology.
Key Responsibilities
Design, execute, and troubleshoot biochemistry and molecular biology experiments
Perform and optimise SELEX experiments, NGS and RT-PCR
Perform and develop our proprietary aptamer selection workflow
Maintain excellent documentation of laboratory work
Analyse, interpret, and present results to present to colleagues in regular meetings
Collaborate with the R&D ML and Bioinformatics teams
Ideal Candidate
Have obtained, or currently finishing, a Ph.D degree in a relevant disciplineÂ
Experience with small molecule SELEX
Experienced in molecular biology, biochemistry, and/or assay development
Hands-on experience with PCR, nucleic acid QC, protein QC (e.g., SDS-PAGE) and analysis
English language speaking, listening and writing fluency
Excellent organisational, data-archiving and presentation skillsÂ
Desired Candidate
Experienced in biophysical characterisation of nucleic acid-protein or nucleic acid-ligand interactions (e.g., BLI, ELISA, FP) is a plusÂ
1+ years industry experience or in partnership with industry (e.g., startup, Pharma)
Publication in a major scientific journal with molecular biology/biochemistry contributions is a plus
About the Company
Read more about PentaBind, our culture and what to expect via the button below.